Introduction. In the context of the pandemic of a new coronavirus infection, crises in the field of economy, education, politics and health have intensified. Medical workers turned out to be the most vulnerable category of the population in terms of the risk of developing emotional burnout. The additional challenges faced by healthcare professionals have multiplied the workload of healthcare professionals, as well as increased susceptibility to stress and burnout. The purpose of the study is to conduct a comparative analysis of the phases of the burnout syndrome among medical workers and to study the factors associated with the burnout syndrome during the COVID-19 pandemic. Materials and methods. The study involved healthcare workers in COVID hospitals (n=201); medical workers of the outpatient-polyclinic level (n=186); medical workers of multidisciplinary hospitals (n=195); control group (n=190). The following research methods were used: a questionnaire survey and a questionnaire by Boyko V.V. «Diagnosis of the level of emotional burnout», which is a questionnaire of 84 questions. Results. A high level of emotional burnout was revealed in the general sample of medical workers compared to the control group. The most pronounced signs of emotional distress: tension, resistance, exhaustion are found in medical workers in COVID hospitals compared to medical workers in multidisciplinary hospitals and outpatient clinics. Potential sources of stress for medical workers include: high workload, restrictive measures being introduced, fear of illness, lack and shortage of PPE, the threat and risk of contracting a new coronavirus infection, a long period of isolation, financial instability, insufficient (in the first stage) accumulated knowledge about a new little-studied disease, a feeling of discrimination and / or stigmatization.

Evaluation of clinical data and features of immunopathogenesis, along with molecular genotyping, open up new possibilities for a personalized approach to the prevention and treatment of occupational bronchial asthma. The aim is to determine clinical, immunological and genetic markers of the risk of developing occupational bronchial asthma under exposure to sensitizing substances based on the results of an assessment of polymorphic variants rs2069812 of the IL5 gene. The study included 170 patients with various phenotypes of occupational bronchial asthma and 50 people in the control group. The levels of MCP-1 cytokines and total IgE in blood serum were determined by solid-phase enzyme immunoassay using standard reagent kits. The serum content of vascular endothelial growth factor (VEGF) was studied by sandwich-type solid-phase enzyme immunoassay. Genotyping was performed by polymerase chain reaction. During the study, the features of clinical and immunological manifestations depending on the phenotype of occupational bronchial asthma were established for the first time, genetic markers of the risk of developing this pathology under the influence of sensitizing substances were identified: polymorphic variants rs2069812 of the IL-5 gene.

Medical workers are a group at increased risk of infection with the SARS-CoV-2 virus when providing medical care in modern conditions. The novel coronavirus infection can be considered as an occupational disease in medical workers if the infection occurred while performing their professional duties. One of the most important complications of the new coronavirus infection is the lesion of the cardiovascular system. The presented clinical case reflects one of the possible serious complications of the coronavirus infection that developed in a medical worker against the background of chronic autoimmune pathology, i.e. severe myocarditis with pulmonary embolism, which led to the formation of inflammatory cardiomyopathy with congestive heart failure. The article presents the principles and results of a medical examination conducted in order to establish a causal relationship between the disease and professional activity.

Doctors and healthcare workers are among the most «burnout» professions. Burnout syndrome occurs when there is physical and emotional exhaustion. During the COVID-19 pandemic, medical workers have the highest psychoemotional burden. Professional burnout can largely affect the efficiency of both the employee and the unit as a whole. Purpose — to investigate the syndrome of professional burnout among medical workers of COVID hospitals; outpatient medical workers and medical workers of multidisciplinary hospitals. A group of medical workers from COVID hospitals (n = 201) was examined; a group of medical workers of the outpatient clinic level (n = 186); a group of medical workers of multidisciplinary hospitals (n = 195), as well as a control group (n = 190). To study the professional burnout syndrome in the presented groups, the Maslach Burnout questionnaire was used. At the stage of the study, it was revealed that medical workers in COVID hospitals have significantly higher rates of «professional exhaustion» and «depersonalization» compared to medical workers in multidisciplinary hospitals (p ≤ 0.001) and outpatient medical workers (p ≤ 0.001). At the same time, medical workers in COVID hospitals have a significantly lower indicator of «reduction in personal achievements» compared to medical workers in multidisciplinary hospitals and outpatient clinics. Thus, in a comparative study, it was revealed that all the studied groups of medical workers, according to the Maslach Burnout test, have increased rates of professional burnout. At the same time, medical workers in COVID hospitals have significantly higher rates of «professional exhaustion», «depersonalization» and lower values of the «reduction of personal achievements» indicator, compared with medical workers in multidisciplinary hospitals and outpatient clinics. Treatment of patients with novel coronavirus infection is a factor influencing the psychological health and professional burnout of healthcare workers during the COVID-19 pandemic.

The pandemic of the novel coronavirus infection has posed additional challenges for endoscopy services. Endoscopy departments face a high risk of spreading airborne respiratory diseases in their daily work. This is especially true for endoscopic departments and offices that perform bronchoscopic examinations. The world scientific community recognizes the highest epidemiological risk of personnel infection during any interventional manipulations and operations related to the respiratory system, including bronchoscopic interventions.