Diabetic foot syndrome is a complex of anatomical and functional changes that develop on the background of diabetic neuropathy, micro- and macroangiopathy, osteoarthropathy, contributing to increased trauma and infection of the soft tissues of the foot, the development of purulent necrotic process and leading to amputation in neglected cases. Diabetic foot syndrome is a collective term that unites a group of late complications of diabetes mellitus, in which pathological changes in the patient's feet develop as purulent necrotic processes, ulcers, and osteoarticular lesions occurring against the background of specific changes in peripheral nerves, vessels, skin and soft tissues, bones and joints. In some cases, the concept of «diabetic foot» is not used as an independent nosological form, but indicates its constituent diseases (abscess, phlegmon, gangrene and others).