Cough is the most common symptom for which the patient goes to a general practitioner. Acute cough, which often occurs with upper respiratory tract infection, can be a serious problem from the very beginning, but usually disappears on its own and rarely requires medical intervention. Chronic cough is the main symptom of many serious chronic respiratory diseases, but it can also be the only symptom of a number of extrapulmonary diseases, especially upper respiratory tract and gastrointestinal tract. Even if the diagnosis is known, cough can be difficult to treat and worsen the patient's quality of life.

Hypoglycemic syndrome is a symptom complex that develops due to an imbalance in the system of maintaining blood glucose levels with the development of hypoglycemia and is stopped by the administration of glucose. A rapid and significant drop in glycemia can lead to a life—threatening condition - hypoglycemic coma. Chronic hypoglycemia leads to irreversible changes in the central nervous system, and forced frequent meals with a high content of easily digestible carbohydrates lead to an increase in body weight up to the development of morbid obesity. Thus, hypoglycemic syndrome is an urgent problem of modern medicine. The most common cause of pancreatogenic hypoglycemia in patients without diabetes mellitus is insulinoma. The causes of hypoglycemic syndrome may also be: exogenous administration of hypoglycemic drugs, severe multiple organ and tumor pathology, consequences of bariatric surgery, deficiency of contrinsular hormones, genetically determined enzyme disorders and autoimmune diseases. The primary diagnostic tasks determining the choice of therapeutic tactics are the confirmation of hypoglycemic syndrome and the determination of its etiology.

Among the modern methods of research of patients with pulmonary diseases, one of the leading places is occupied by the study of the function of external respiration. The growing interest in these research methods among general practitioners is associated with an expanded understanding of the mechanisms of development, the development of diagnostic criteria, including early diagnosis of chronic obstructive pulmonary disease.

Ischemic heart disease is a myocardial lesion caused by impaired blood flow through the coronary arteries of atherosclerotic origin. The concept of «coronary heart disease» includes both acute (unstable) and chronic (stable) forms. In the Russian Federation, the mortality rate from coronary heart disease remains higher than in Europe and America, which is associated with insufficient adequacy of monitoring and treatment. In addition to coronary artery stenosis, other factors play a role in the development of the disease, including the effectiveness and timeliness of observation and monitoring. New portable devices and devices can be used for auxiliary diagnostic measures in case of coronary heart disease. RaDoTech is a portable electrodiagnostic device that allows you to dynamically monitor the state of the body. Early detection of changes allows you to start treatment or correction immediately, which increases the chances of recovery and minimizes the risk of complications. This is especially important in the case of chronic coronary heart disease, when early intervention can prevent progression and improve quality of life. The Angiocode-301 minicardiotracker determines indicators that identify possible disorders among patients suffering from coronary heart disease. Its data can be useful for doctors in diagnosing and monitoring the condition of patients.

Timely diagnosis and early initiation of adequate therapy of anxiety spectrum disorders remains one of the urgent tasks of modern medicine, which is determined by the high prevalence and significant impact of anxiety disorders on the quality of life not only of somatically burdened patients, but also physically healthy people. The article discusses aspects of the diagnosis and treatment of anxiety disorders by a general practitioner.

Edema is an excessive accumulation of fluid in the tissues of organs and serous cavities, manifested by an increase in tissue volume and a decrease in the capacity of serous cavities, a change in physical properties (turgor, elasticity) and a disorder of the function of l=edematous tissues and organs. Edema forms as a result of the accumulation of excess fluid in the interstitial space. The causes of edema are different and require differential diagnosis in order to determine treatment tactics. A personalized approach to the treatment of peripheral edema improves the prognosis of the disease and improves the quality of life of patients.

World Health Day is celebrated on April 7. The healthcare system is presented in the format of a basic factor contributing to better health. According to tradition, health care focused on sick people was integrated directly with her. Accordingly, the available social and medical resources were addressed to them. The set of risk factors affecting the state of health has taken the limits associated with the organization of health care itself. At the beginning of the XXI century, narratives were approved: «1) The causes of modern pathology are the way of life of a person. 2) The problems of studying, preserving and restoring public health are becoming the most urgent in modern conditions due to the following reasons: a) increased health effects of various biological, b) socio-economic, c) psychological factors, those associated with scientific and technological progress, with the urbanization of society [8]. The narrative of stimulating the patient's own participation in the treatment process implies an increase in responsibility for their own health. At the same time, the leading «party» is played by behavioral risk factors [1, 3, 8], the peculiarities of the lifestyle of patients, various factors in the format of health formation, attitude to the preservation and promotion of health. The stereotypical opinion that «health» is equal to a list of diseases that require medicines to eliminate, rather than indicators of a healthy lifestyle, caused the conjuncture of reorientation of public consciousness to a completely different narrative: «Not the treatment of emerging diseases, but the protection of the health of a healthy person,» which makes it possible to form the right attitude to health from childhood, — the concept of «health preserving behavior».

In the case when the right hemisphere of the brain is dominant, a person develops left — handedness — it is more convenient for him to write with his left hand, use cutlery, open doors, give his left hand for a handshake. There are not so few such people — according to statistics, 10–15 % of the world's population is left-handed, and most of them are among the Anglo-Saxons. Left-handed people have always aroused special interest and some wary attitude of others, aroused surprise and curiosity. During the Inquisition, all those who used the left hand as the main one were considered «servants of Satan» and were persecuted. In modern society, there is a more tolerant attitude towards such individuals, but still left — handers have to face a number of difficulties in their lives — most subjects in this world are created for right-handers, and the left-handed half still find it difficult to adapt to society because of the «right-handed» social orientation. Most of the various household appliances, handrails in transport, production machines at enterprises and so on are made for the right hand. It is more difficult for left-handers to adapt to such mechanisms, therefore, there are more cases of occupational injuries among left-handers. The inconveniences that lefties experience from daily, every-second use of all this, scientists have called decompression. And at the initiative of the British Left-Handed Club, on August 13 it was proposed to recognize the World Day of Those for whom the left hand is dominant.