The work presents a pressing problem for doctors of any specialty — burnout syndrome. It is important to be able to prevent the development of burnout and overcome it correctly. Rationale. This problem is generally recognized. Meanwhile, in the literature these issues are reflected somewhat scatteredly; there is no systematization. Purpose. Considering the sources by Russian and foreign authors aimed at studying the relationship between doctors’ burnout and the coping strategies that they use. Methods. A literature search of Russian and foreign authors was carried out; the obtained data were analyzed and summarized. Results. In the course of working with a patient, the doctor is involved in this process not only as a specialist demonstrating his/her professional skills and curing this or that pathological condition, but also becomes involved emotionally. Moreover, if, when working with a patient, the doctor is emotionally invested in the situation more than the patient himself/herself and chooses an interpretative or paternalistic model of relationship, this will contribute to the development of burnout and, over time, in the absence of preventive measures, lead to the burnout progression. In this regard, a doctor of any specialty must remember it and select these models of interaction with the patient as a last resort and for a short time, or use these models at the very beginning of the disease, when the patient cannot yet accept his/her new condition. A major role in resolving this issue is played by informing specialists about the early signs of burnout and risk factors, getting emotional support from colleagues and management, and taking training sessions aimed at acquiring skills to cope with stressful situations. Conclusion. Despite the fact that burnout has been known and actively studied for many years, and that there has been some success in solving this issue, the problem is still relevant in modern society among specialists whose work activities are carried out in the person-to-person sphere, primarily among doctors. The use of coping strategies will improve the level of psychological health of the employee and the effectiveness of the provided assistance and reduce the prevalence of iatrogenics.

The article describes the features of the quality of life in vibration disease from exposure to local vibration and its combination with osteoarthritis. It has been proven that when exposed to industrial vibration, there is a change in all indicators characterizing the quality of life, which is most pronounced in second-degree vibration disease from exposure to local vibration and its combination with osteoarthritis.

The phenotypic manifestation of the neurophysiological level of regulation of human visual perception has numerous forms. Dyslexia is a neurological disorder associated with a selective impairment of the ability to master reading and writing skills while maintaining overall learning ability. There are two priority approaches to studying the issue of dyslexia — phonological and visual approaches. This study considers visuospatial disorders, visual information planning disorders, scotopic sensitivity syndrome, features of visual gnosis, visuomotor disorders, and dyspraxia. At the age of 5–6, children begin to develop the skills of writing and reading; for some, this process goes easily and the child does not experience difficulties in mastering these processes. Meanwhile, some children have difficulties in mastering reading and writing even at 8–9 years of age. The features of the brain mechanisms underlying the processes of reading and writing were studied using the EEG method and neurodiagnostics, and the most effective correction methods at the neurophysiological and pedagogical levels were recommended. The findings from these studies expand our understanding of how neurophysiological mechanisms influence learning difficulties in children with normal IQ levels. This has important implications for our ability to effectively correct and prevent such problems.

The article describes the features of the state of the immune profile and cytokine regulation in vibration disease associated with exposure to local vibration and its combination with osteoarthritis. The prognostic value of changes in the immune profile and cytokine regulation in vibration disease from exposure to local vibration and its combination with osteoarthritis has been established. It has been proven that when exposed to industrial vibration, there is a change in the main indicators of cellular immunity and cytokine regulation, which characterize the state of the immune system in vibration disease from exposure to local vibration. Notably, these changes are most pronounced in second-degree vibration disease from exposure to local vibration and its combination with osteoarthritis.

An analysis of external respiration indicators and quality of life of patients with different phenotypes of occupational asthma was carried out (according to the analysis of the results of the MOS SF-36 questionnaire). In the patients with all phenotypes of the disease, there was a decrease in forced expiratory parameters in all phenotypes of occupational bronchial asthma, as well as in indicators of both mental and physical health relative to the control group (p<0.001). Notably, the worst indicators of quality of life were demonstrated by the patients with the phenotype of occupational asthma with metabolic syndrome. The individuals in this group had the lowest average scores on 6 out of 8 questionnaire scales, and significant differences were confirmed on 5 scales: these are the scales of physical functioning, general health, vital activity, social functioning, and role functioning due to emotional state. The quality of life was least affected in the patients with non-allergic phenotype of occupational bronchial asthma: the results of this group turned out to be the best among the patients with all disease phenotypes on 5 scales, and the patients scored significantly the highest on 4 of these scales.

Brucellosis is an infectious disease; the causative agent is bacteria of the genus Brucella, which are transmitted through meat and dairy products and affect the osteoarticular, cardiovascular, and nervous systems. Laboratory diagnostics includes methods of molecular genetic testing and serodiagnosis.