The opinions of international experts on African swine fever and approaches for prevention and elimination of this decease in compliance with the international standards have been presented up in the article. The data on FAO international technical assistance to the Republic of Belarus to eliminate African swine fever outbreaks have been stated.

The results of laboratory investigations to determine the etiological structure of E. coli strains isolated from pathological material taken from calves of the first days of life belonging to agricultural organizations of the Republic of Belarus unfavorable for infectious enteritis have been presented in the article. Despite the widespread immunization of down-calving cows and heifers against colibacteriosis (escherichiosis) of calves using vaccines designed by O-antigen selection colibacteriosis (escherichiosis) ranks first among factor diseases of young cattle in terms of the number of disadvantaged points, the number of sick and dead animals, which can be explained by the discrepancy between the antigenic structures of vaccine and epizootic strains.

The purpose of the research was to monitor the epizootic situation, as well as to determine the etiological structure of colibacteriosis of calves in different regions in the Republic of Belarus in the period from 2015 to 2019. It was found that colibacteriosis has been leading among bacterial gastrointestinal diseases caused by opportunistic microflora for a long time. The number of disadvantaged points from 2015 to 2019 ranged from 151 to 231 units. The number of sick animals ranged from 493 to 869 animals. The mortality rate reached up to 66,3 %. Most of the strains circulating in the farms of the Republic of Belarus from 2002 to 2009 and from 2015 to 2019 virtually unchanged. In addition, there are new strains obtained from bacterial cultures that are not typed with the O-coli serums included in the diagnostic kit, and their number was 46,35 %.

The aim of the research is to study the dynamics of hematological parameters of piglets in a state of hypotrophy and its correction with Sedimin®. The article presents the results of studies of hematological parameters of piglets of a large white breed of 5 days of age in a state of hypotrophy and its prenatal correction. The use of the Sedimin® complex preparation to sows had a positive effect on the physiological and biochemical composition of piglets’ blood – an increase in the number of erythrocytes and total leukocytes at the hemoglobin level, the concentration of total protein and albumins, which contributes to the regulation of metabolic processes and has a preventive effect in case of antenatal hypotrophy of piglets.

The traits of nanostructured AEKol have been presented, the sizes of nanoparticles in various shells have been found, and self-organization has been also investigated. It has been shown that the size of the nanostructured AEKol did not significantly depend on the nature of the shell and ranged from 206 to 351 nm, and the polydispersity coefficient already depended on the nature of the shell and ranges from 1,46–1,99–2,07 for sodium alginate, agaragar and carrageenan, respectively, which corresponded to the spherical shape of nanocapsules, and in konjac gum and xanthan gum it had a value of 3,85 and 6,92, which corresponded to the ellipsoid shape. The research of the supramolecular properties of nanostructured metal oxides has shown that self-assembly of nanoparticles was possible due to non-covalent interactions, as the result of which self-assembly was characteristic of them.

Spread antibacterial therapy, which carried out according to therapeutic and preventive schemes is considered to be a highly effective and the most rational tool for controlling infectious diseases under the conditions of large industrial pig breeding enterprises. It has been found that long-term intramuscular use of the drug Tulatrin in a therapeutic and three-fold therapeutic dose did not have an expressed pathological effect on the body of pigs. During the experiment, no animal dead and manifestationed of clinical signs of intoxication (depression, vomiting, salivation, diarrhea, etc.) have been noted. The animals were active and had feed intake well. The live weight of piglets in the experimental groups did not significantly differ from the animals that were housed in the control groups. The liver was the most sensitive to the action of tulatromycin with prolonged intake of the drug in elevated doses, which has been confirmed by the results of biochemical studies. However, the intrinsic hepatotoxicity associated with the use of high doses or prolonged use was characteristic of all drugs of the macrolide group. It should be noted that in this case, the maximum increase in marker liver enzymes did not exceed 10 % of the upper limit of the norm, so we could say that the liver damage was of a trace nature, since the clinical significance was the increase in liver samples by at least 2 times. Also, the increase in total protein was not fatal and did not affect the change in the clinical status of the animals. We did not note the death of animals and the manifestation of clinical signs of intoxication and hepatopathy. Tulatrin is one of the safe medicines, and is characterized by good tolerability. The results obtained confirm the safety of using the drug in the recommended dosage regimen.

Today more and more consumers around the world prefer goods and services with improved characteristics according to their impact on the state of the environment and human health. The purpose of the study was to analyze the criteria for assessing the environmental safety of plant products. The criteria for assessing the environmental safety of plant products include regulatory indicators (DSTU), as well as evaluation criteria for obtaining environmental labeling (these include environmental criteria for assessing the life cycle). Environmental criteria for life cycle assessment contain 23 additional state standards of requirements for the management system of environmental aspects of production and environmental pollution indicators, as well as for raw materials, finished products, their packaging, labeling and consumer information. The products of plant origin, their components (raw materials, ingredients, components, etc.) and the impact on the state of the environment and human health associated with its life cycle are evaluated. This approach distinguishes environmental certification from the traditional approach to evaluating products for compliance with technical conditions or safety indicators. The features of the criteria for assessing the environmental safety of products of plant origin, and also indicates the need for labeling products have been highlighted in the paper. A comparative analysis of international certifications of the ISO level and state standards (Federal standard type) has been presented in the paper. A comprehensive analysis of the differences between environmental and organic certification has been provided in the paper.

The influence of highly structured silicon containing zeolite enriched with the amino acid complex VitaAmin on the general state of the body and productivity indicators in dairy cows and calves has been studied. The object of the investigation for the fulfillment of this purpose cattle of Black-and-White breed has been selected. The first group was control; the second was experimental with the introduction of additives into the ration. As the additive natural zeolite from the Yushanskoye deposit in the Ulyanovsk region has been used, this was subjected to technological processing in factory conditions. A new technology of activation, structuring, dehydration, and enrichment of zeolite with amino acids has been used. This is the additive of purely natural origin; it does not contain chemical components. In young animals the average daily gains in live weight has been increased by 14,9 % compared with the control group. The average daily milk yield of cows during the experiment was 24,7 kg of milk compared to 20,88 kg in the control group. The increase was 3,82 kg per day, during the experiment 0,687 tons of milk was obtained additionally due to the use of the additive. Under its influence the processes of milk synthesis, metabolism, and anabolic processes in young animals are activated in the body of cattle.