Measures to fight rabies include preventive immunization of domestic and farm animals, oral vaccination of wild carnivores, trapping of stray dogs, as well as measures to regulate the number of wild animals. Vaccination allows us to form an immune layer among animals, which will further prevent the spread of rabies and reduce their incidence. The reservoir and the main source of the rabies causative agent in the Republic of Tatarstan are mainly wild predatory animals. The purpose of these studies was to establish the dependence of the detection of rabies cases among agricultural animals in the Republic of Tatarstan from anti-epizootic measures carried out in the wild fauna. Statistical data have been processed on the following indicators: habitat of foxes, population density, volumes of antiepizootic measures (population regulation and volumes of oral vaccination). Data on the total number of detected cases of rabies in domestic, agricultural animals and animals in the wild fauna were studied for the period from 2013 to 2018. Given the fact that the largest number of detected cases of rabies in the wild fauna falls on foxes, information has been analyzed on the relationship of preventive antiepizootic measures with the number of cases of rabies detected in them as well as the detection of rabies cases in domestic and agricultural animals. It has been found that with the increase in the number of oral vaccines used for laying in wild animal habitats in conjunction with measures to regulate their numbers since 2015 the number of detected cases of fox disease has decreased. This has been also reflected in the decrease in cases of rabies detection among domestic and agricultural animals.

The work has been carried out in the Department of particularly dangerous infections, wich execute veterinary and sanitary control in order to prevent the occurrence and spread of particularly dangerous infections for human and animals (Moscow city). The anthrax diagnostic included microscopy of smears from the sample material, culture media growth, basic and additional identification tests, use of fluorescent antibody method (MFA) to detect antigens and antibodies, PCR, bioassays and precipitation reactions. The researches of pathological material, meat, leather raw materials, sanitary washouts have been provided in the period 2017–2018. All assays allowed us to confirm total absence of B. antrhacis in the studied samples. Consequently, the epizootic and epidemic situation of anthrax in the territory of Moscow city in 2017–2018 years remained favorable.

The purpose and objectives of the study were to compare antiparasitic effectiveness of coccidiostatics of amprolium of 25 % and baycox of 5 % at an eimeriosis in calves. The infectiousness of calves by oocysts of eimeria has been diagnosed in one of the farms in the Ivanovo region. Fecal samples have been selected at clinically sick calves (profuse diarrhea, in excrements slime, vials of gas, blood; the general oppression has been found, refuse of forage, rise in temperature to up 40–41ºС) from a rectum on 10–15 grams from each animal have been observed and have been located in disposable containers where specifi ed age, sex of an animal and the time of collecting. The material has been investigated in the laboratory of Department of Infectious and Parasitic Diseases named after Academician of RAS Yu.F. Petrov by the method of Fyulleborn. For the assessment of therapeutic eff ectiveness of drugs two groups of calves 2–3 months of age to 10 heads in each were picked up for the principle of analogs. The animals of the first group (calves of 3 months of age) has been got amprolium 25 % of BT in a dose of 0.04 grams on 1 kilogram of weight the course of 5 days in a row processed once a day. To the calves of the second group of 2 months of age 5 % baycox has been given in the form of suspension, inside in the dose of 15 mg/kg at the rate of 3 ml on 10 kg of live weight, once. The drugs have been given in a mixture with warm water, individually in morning feeding. The daily clinical observation for the animals throughout all treatment has been conducted. As a result of the researches on the farms having the cases of eimeriosis of calves with the preventive purpose we recommend to treat once a month, starting since 20th day to 6 months of age inside and individually, once baycox 5 % in the dose of 15 mg/kg on AS. Along with chemoprophylaxis the disinvasion of rooms and objects of care of animals (to achievement by calves of 6 monthly age once a month) is recommended to be carried out.

Representatives of the genus Echinacea (Echinacea Moench) have a number of valuable properties, especially such as stimulation of immunity. In this regard, drugs and food products created with use Echinacea are being mandatory for the correction of immunosuppressive conditions.

The disease of cows with mastitis leads to reduce of milk production and is often the reason for culling of animals. Treatment of mastitis begins after the appearance of characteristic signs of the disease the increase and tenderness of the affected udder parts, changes in the organoleptic properties of milk. Early diagnosis and timely treatment and preventive measures can reduce the incidence of dairy herd and avoid economic losses from this disease. Under the conditions of dairy farm JSC “Rodina” in the Zhukovsky district in the Bryansk region studies of the effectiveness of diagnosticums “Masttest”, “Ecotest” and “Cenotest” to detect mastitis in cows have been carried out. According to the results of laboratory studies the evaluation of the quality of milk from sick animals has been given. The biggest diagnostic efficiency belongs to the “Cenotest”. This drug has been revealed 94.4 % of cows with subclinical mastitis. Most cows suffer from subclinical mastitis at the end of the lactation period as well as at the age of 7 years. Laboratory studies of milk from cows with clinical and latent mastitis have been carried out. In cows with subclinical and clinical form of mastitis there is a decrease in protein by 2,2 and 16,4 %, respectively, an increase in acidity by 3,6 and 8,6 %, an increase in conductivity by 21,3 and 54,5 % in relatively healthy animals. The content of lactose and dry skim milk residue in cows with clinical mastitis has been decreased by 10,6 and 10,65 %, respectively, compared with the control group of cows. The average number of somatic cells in cows with subclinical mastitis was 674 thousand/ml, in patients with clinical form of mastitis >1500 thousand/ml.

The data characterizing the correlation of different types of eating behavior with the live weight and fertility of Tuvan sheep have been provided in the article. We have established that animals of the first type of behavior exceed in the live weight of animals of types II and III. At lambing the count of off spring has been recorded and a high percentage of fertility of the fi rst type (110 %) has been found, and the ewes of the II and III types of behavior have had 105 and 98 %. The presented data on the distribution of behavioral groups indicate a high specifi c gravity of the I strong balanced type in the experimental group, in this connection it is expedient to use the type of food reaction of sheep as a breeding trait when selecting the breeding stock for sheep farms.

Under the modern conditions there are increasingly high requirements for microbiological indicators of milk quality, which are reflected in the latest regulations and is one of the important conditions, compliance with which is taken into account when accepting the product for further processing. As practice shows high microbiological contamination and increased content of somatic cells in milk are often the reason for the discrepancy of its quality to modern requirements refl ected in national and international regulatory documents. The development and implementation of measures aimed at improving the condition of the udder of cows in connection with the use of modern means of its processing is one of the important tasks to improve sanitary and hygienic conditions in the production of milk. It is well known that the most affordable way to prevent mastitis is strict observance of hygiene rules during milking. Prevention of mastitis preserves the health of the animal, increases the duration of use of the cow, improves the quality and safety of milk and dairy products, increases the economic efficiency of milk production and increases the interest of specialists in agricultural business. The results of research work, which have been obtained on a dairy farm, have been presented in our article. During the experiment the udder of lactating cows has been treated with modern domestic means. For this purpose one control and two experimental groups have been formed in farms. During the lactation period the udders of cows in experimental groups have been treated with special detergents and disinfectants. In the control group the udder has not been treated with special means: its purity was maintained by washing with warm water, as was usually customary in the economy. It has been found that the treatment of cows udder disinfectants helps to reduce microbiological contamination and reduces the number of somatic cells in the milk of cows.

The purpose of our research was to assess the quality of canned fish of domestic producers. The objects of examination were canned fish: herring Pacific natural with the addition of oil brand “Dobroflot” and mackerel Atlantic natural brand “Sea luck”. The studies allow us to conclude that these canned fish are produced in compliance with all stages of the technological cycle and taking into account the principles of the HACCP system and comply with the requirements of regulatory and technical documentation, in particular GOST 13865-2000 “Canned natural fish with the addition of oil. Technical conditions». Canned fish of these brands have good sanitary qualities and are safe for human use. In general, producers offer us a fairly high-quality product.

The veterinary and sanitary examination, the results of microbiological analysis of the contamination of milk and sour cream in the bottling process, and contamination of sour cream (as a finished product), pasteurized milk and granulated curd have been considerate in the article. According to the results of the analysis in the both samples of sour cream (bottled and finished product) has not been observed deviations from the norms. On the basis of the analysis, it can be said that the sour cream with a fat content of 20 % (GOST 31452-2012) is of high quality and ecologically safe for microbiological indicators. Conducted research of the milk, sour cream and curd in the process of packaging and directly in the finished products has not been shown any abnormalities in the taken samples. Thus, the study revealed that dairy products manufactured by LLC “Tyvamoloko” have a high quality and environmentally safe in terms of microbiological indicators. The technological requirements of producing and the sanitary and epidemiological state at the enterprise are fully respected.

Approbation and comparative tests of test-plates designed to count the number of mesophilic aerobic and facultative anaerobic microorganisms (QMAFAnM) in poultry products have been carried out. Laboratory tests included identifying the sensitivity ranges of test plates for determining QMAFAnM, calculating the percentage of their recoverability (% germination) from the surface of the test-plates, as well as conducting their comparative tests using the classical analysis method. Type 1 test-plates contain ready-made nutrient medium, gel and tetrazolium indicator; they are used to calculate QMAFAnM in food samples, food raw materials, and also when monitoring the environment. Type 2 test-plates are intended for express counting of QMAFAnM in food products and environmental objects; they contain ready-made nutrient medium, a water-soluble gelling agent and a color indicator. When comparing the sensitivity of classical media and type 1 and type 2 test-plates when determining QMAFAnM, a high sensitivity of both nutrient agar and test test-plates has been established. For solid media, it is at least 0,1 ml of a suspension of 6 dilutions. In our studies the growth of typical colonies has been revealed on all plates and test-plates from 6 and 7 dilutions, which indicates high sensitivity. The recovery rate on the test-plates has been found to be good: 98,9 % on type 1 test-plates and 86,8 % on type 2 test-plates. In a comparative study of the classical method and test-plates a good result has been obtained. In all cases the results of studies on QMAFAnM test-plates are comparable with the classical method: the percentage of extractability of the tested material was more than 80 %, in some cases even 100 %. Test-plates for determining QMAFAnM are easy to use, reliable, have a long shelf life (1 year), with their use, the analysis time is reduced, and the complexity of research is reduced.