The results of definition of genotypes according to the marker genes MC4R, PRLR, ESR, FSHb, RYR1 and PIT1//MST in relation with reproductive ability of sows under conditions industrial pig breeding complex have been given. It has been established that according to MC4R gene the highest reproductive performance were sows of genotypes GG and AA: prolificacy was 11,0 and 11,31 piglets, weight of the litter of piglets at birth was 12,98 and 12,89 kg, heavy litter was 1,13 and 1,14 kg, the number of piglets at weaning at 26 days was 10,6 and 10,56 heads, respectively. According to gene PRLR leading position in productivity held sows with BB genotype: prolificacy was 11,81 piglets, weight of the litter of piglets at birth was 13,41 kg, the number of piglets at weaning was 11,10 heads. According to gene ESR with higher productivity had AB-sows: prolificacy was 11,07 piglets, weight of the litter of piglets at birth was 12,53 kg, the number of piglets at weaning was 10,47 heads, the livability of the young animals to weaning was 94,58%. According to FSHb gene the best reproductive productivity was inherent in the sows of AB genotype: prolificacy was 11,53 piglets, weight of the litter of piglets at birth was 13,24 kg, heavy litter was 1,14 kg, and number of piglets was 10,89 heads. According to gene PIT1//MST the best productivity had sows CD genotype: prolificacy was 12,0 piglets, weight of the litter of piglets at birth was 13,47 kg, heavy litter was 1,13 kg, number of piglets at weaning was 11,0 heads. According to RYR1 gene all 100% of sows had the NN genotype.

The increase of productive longevity of Holsteinized cows of Black-and-White breed under the conditions of breeding farm Druzhba of the Koshkinskiy district of the Samara region taking into account genetic factors and to determine the possibility of using optimal parameters in the breeding work has been studied. The obtained data on milk productivity and duration of economic use of cows of local population of cattle of Black-and-White breed demonstrates the feasibility of using in the paternal herds of sires with the potential productivity of mothers 7001–9000 kg with moderately heterogeneous type of assorting mating. The analysis of lifetime milk production has been found greater superiority of the progeny of Reflection Sovereign line. For the whole period of their economic using was obtained 20 672 kg of milk in average. The second place was occupied by animals of line Montvic Chiftain with the yield for lifetime 17 229 kg of milk. The best part of blood of Holstein breed is 37,5 per cent to improve productive longevity of cows.

Chemotherapy drugs, which are used for the prevention and treatment of animals not always, give the desired results. One of the safe, environmentally friendly drugs is succinic acid. A wide range of properties of succinic acid can be attributed not only to the biostimulants, but also to medical and preventive preparations. So, succinic acid is one of the main components of the feed mixture Energy. The study of feed mixtures Energy as a therapeutic and prophylactic agent for gastrointestinal diseases of calves at early age has been carried out. In the complex treatment of diarrhea in calves of the early age Energy helps to activate protective forces of the organism, increases bactericidal, phagocytic, and lysozyme activity of the blood, that contributes to more rapid recovery of calves.

The article presents the results of researches of growth and development of bulls and heifers of Hereford and Aberdeen-Angus breeds. The characteristic of the animals with the use of such indicators as a growth factor, growth rate, constant growth, intensity of formation, uniformity of growth, and intensity of growth of animals has been given. The growth dynamics of animals in Trans-Ural region has been studied. The change in live weight of young bulls and heifers from birth to 15 months of age has been analyzed; absolute, relative growth and average daily gain their live weight have been calculated. It has been found that animals of Hereford and Aberdeen Angus breeds had higher values of the indicators characterizing their growth and development. Minor deviations from the norms of some indicators, such as average daily gain, uniformity of growth, can be eliminated by improving the conditions of management and feeding of animals.

The wool productivity of camels is a source of additional income, which can be received from farms of camels. Camels have uniform soft wool, which has a high heat capacity and durability. A study of the wool productivity of camels Mongolian Bactrian breed in different climatic zones of the Republic of Tyva (forest-steppe and dry-steppe) has been carried out. It has been found that average wool clip in camels Mongolian Bactrian breed is increased from 1900 in the year of age up to 6400 g in a mature animal. The value of the fleeces is influenced by the conditions of the winter maintenance, the condition of fatness, and loss of hair during moulting. There is with age an increase in wool productivity, but reduced the output of soft fibers, and the number of coarse fibers in fleece increases. So, at age of year the output of down in females is from 71,2 to 74,1%, depending on the type of wool and zone of breeding camels, at the mature animals output of down is 67,2 and 70,2%.

The study of the dynamics of the components of energy metabolism in a developing organism is necessary for judgments about the adaptation possibilities of organism of sheep in adopting and carrying out organizational measures on elimination of iodine deficiency in sheep farms located in areas with a lack of this trace element. Researches on the sheep of Karachai breed rearing in different natural-climatic zones, on the one hand, with unequal iodine availability from the other have been carried out. Objective laws of ontogenetic peculiarities of formation of the energy metabolism of sheep kept in different natural-climatic zones, with different iodine availability have been found. The possibility of correction of violations of lipid-carbohydrate metabolism by thyroxine has been proved.

The ability of animals to realize their biological potential depends on many factors, in particularly on the state of nonspecific resistance. Natural resistance expresses the ability of an organism to resist the adverse effects of environmental factors on the genetic level. The effect of integrated use of immunomodulators Gamavit and Eleutherococcus Extract in different dosages on the level of natural resistance of Holstein cattle of Black-and-White breed of the German selection has been studied. It has been established that the level of nonspecific immunity is influenced by such factors as the period of increasing the milk yield and the use of drugs that exert an equivalent influence. For example, the factor of the period of increasing the milk yield has influenced by 12.85%, and factor the use of drugs by 12,21%, the combined effect of these factors made up by 12,36%.

The testing of new drug Hydro peptide with iodine for the prevention of obstetricgynecologic diseases and infertility in cows has been conducted. It has been established that the appointment to cows of Hydro peptide with iodine reduces the time of recovery of animals and recovery of reproductive ability. In the experimental group of cows compared to the control group time from calving to insemination was shorter by 23,6 days (P < 0,001). In the experimental group were fertilized 14 heads (60,9%), whereas in the control 7 heads (41,2%) for 4 months. In the experimental group of cows in the first stage of excitation of sexual cycle 10 heads (43,5%) have been fertilized, in the control significantly lower 3 heads (17,6%). The shortest period of infertility in cows was observed in the experimental group, the shorter by 23,5 days (P < 0,001) compared with the control group. The insemination index in the experimental group was 1,29, against 1,71 in control group.