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УДК: 616–036.22 DOI:10.33920/med-08-2106-01

Seasonal fluctuations C. pneumonia and M. pneumoniae infections among children with acute respiratory diseases

Kebak Vera A. leading biotechnologist, Department of Bacterial Infections ELISA of JSC «Vector-Best», 630559, Novosibirsk region, Koltsovo work settlement, Research and Production zone, building 36, e-mail: kebak@vector-best.ru, https://orcid.org/0000-0002-0678-4809
Krotov Sergey А. Head of the Department, Department of Bacterial Infections ELISA of JSC «Vector-Best», 630559, Novosibirsk region, Koltsovo work settlement, Research and Production zone, building 36, e-mail: krotov@vector-best.ru, https://orcid.org/0000-0003-3240-5005
Kukhtinova Natalia V. Candidate of Medical Sciences, Associate Professor of the Department of Pediatrics, SBEI VO NSMU of the Ministry of Health of Russia, 630091, Russian Federation, Novosibirsk region, Novosibirsk, Krasny Prospekt, 52, e-mail: Natalya_kuhtinov@mail.ru, https://orcid.org/0000-0003-3593-173X

The article presents the results of the analysis of the main trends in the epidemic process for mycoplasmal and chlamydial infections among children with respiratory diseases over several seasons from November 2018 to July 2020 based on the results of testing 617 serum samples. The data obtained indicate that, along with seasonal fluctuations in seropositivity, there is an epidemiological season from December 2019 to January 2020, characterized by a peak increase in the number of seropositive cases, the largest number of which was detected among school-age children hospitalized for community-acquired pneumonia.

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Conflict of interest. The author declares that there is no conflict of interest.

Financing. The study had no sponsorship.

1.00If a controversial result was obtained, thesample was re-examined to eliminate errors atthe analytical stage.All serological tests were performed in thesame laboratory by qualified personnel.Statistical calculations were verified usingStatistica, version 6.1. The significance of differences between the study groups was checkedusing the χ2 test. The criterion of statistical reliability was the level p <0.05, p for the trend according to the criterion χ2 = 0.086.

1.00If a controversial result was obtained, thesample was re-examined to eliminate errors atthe analytical stage.All serological tests were performed in thesame laboratory by qualified personnel.Statistical calculations were verified usingStatistica, version 6.1. The significance of differences between the study groups was checkedusing the χ2 test. The criterion of statistical reliability was the level p <0.05, p for the trend according to the criterion χ2 = 0.086.

1.00If a controversial result was obtained, thesample was re-examined to eliminate errors atthe analytical stage.All serological tests were performed in thesame laboratory by qualified personnel.Statistical calculations were verified usingStatistica, version 6.1. The significance of differences between the study groups was checkedusing the χ2 test. The criterion of statistical reliability was the level p <0.05, p for the trend according to the criterion χ2 = 0.086.

The rapid increase in the number of factors affecting the nature and degree of threats to sanitary and epidemiological well-being is a trend of the modern stage of human development. Today, the world community faces such challenges as new and recurring infectious diseases, threats of illegal use of synthetic biology products. These problems revealed the need to strengthen control measures over infectious diseases as an effective tool for preserving and strengthening the health of the population [1]. Clear trends of the change in manifestations of the epidemic process of certain nosological forms of infectious pathology require the development of improved approaches to the arrangement and maintenance of epidemiological surveillance of infectious diseases, and serological monitoring should be considered as its most important element. This method makes it possible to assess such important elements as the true immunologic population response to certain pathogens, identify risk groups for the disease and evaluate the effectiveness of existing therapy and prevention algorithms to optimize the use of health care resources [2, 3]. Currently, in the Russian Federation, as in most countries of the world, except China and Japan, serological monitoring of chlamydial and mycoplasma infections is not carried out, which makes works in this direction especially urgent. Carrying out such studies in the era of a pandemic acquires additional importance — assessing the likelihood of a seasonal increase in possible coinfection as a factor that changes the course of the current respiratory disease and patient management tactics.

Для Цитирования:
Kebak Vera A., Krotov Sergey А., Kukhtinova Natalia V., Seasonal fluctuations C. pneumonia and M. pneumoniae infections among children with acute respiratory diseases. Санитарный врач. 2021;6.
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