Motherwort grows on wastelands, along roads, in gardens and pastures. It is a perennial plant with a 1,5 m height. Motherwort contains flavonoid glycosides such as rutin, apigenins, quercitrin, hyperoside; tannins up 2.5%, iridoid glycosides; alkaloids such as choline, stachydrine and nitrogenous bases. [1]
It is an effective remedy for the treatment and preventing heart diseases. Motherwort is also used for treating epilepsy, Graves' disease, thrombosis, gastrointestinal disturbances. It stimulates the smooth muscles of the uterus. It helps with insomnia, neurosis, hysteria, high anxiety, fear and panic bouts, and relieves headaches and neuralgic pains. Motherwort has a similar effect on the central nervous system as Valerian.
This paper continues our research on nanostructured biologically active compounds [2-11]. It is known that nanoobjects have high bioavailability which is used in medicine and pharmacology.
There is no research on studying nanostructured motherwort extract.
The size of capsules containing biologically active compounds affects their physiological activity in the body. [12] The example of many medical substances indicated that reducing particles sizes leads to changes in bioavailability and effectiveness. [13]
In 1987 Jean-Marie Lehn as one of the creators of supramolecular chemistry suggested terms self-organization and self-assembly to describe how molecules adjust in high-molecular composition systems under equilibrium conditions, in particular DNA formation. Lehn defined supramolecular chemistry as the chemistry of molecular assemblies and intermolecular interactions, i.e. the chemistry beyond molecules. This definition is vivid but not entirely accurate. The formation of intermolecular interactions has an impact on the structure of the molecules, which are part of the assembly. Many reactions of self-organization and self-assembly are known due to the different types of interactions when large molecules and molecular assemblies are created. A classic example is DNA and different complex compounds such as host-guest. If the process occurs in solution, then we're dealing with clathrates or inclusion compounds in general. They can be in a more solid-state, for example, clathrate hydrates (gas hydrates). The components can be crown ethers, cryptands, iodides, spherulites, cyclodextrins and others. [14]