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УДК: 616.89 DOI:10.33920/med-01-2512-07

Гендерные особенности течения постковидного синдрома (обзор литературы)

Андреева Ирина Юрьевна аспирант кафедры психиатрии и наркологии, ИКМ им. Н. В. Склифосовского, ФГАОУ ВО «Первый Московский государственный медицинский университет имени И. М. Сеченова» Министерства здравоохранения Российской Федерации (Сеченовский Университет), 119991, Москва, ул. Трубецкая, д. 8, стр. 2, 8(920)2366650, ir_kadochnikova@mail.ru, https://orcid.org/0009‑0003‑6719‑9771
Дмитрий Федорович Хритинин доктор медицинских наук, академик Российской академии наук, профессор кафедры психиатрии и наркологии Института клинической медицины им. Н.В. Склифосовского, ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» (Сеченовский университет) Министерства здравоохранения Российской Федерации, ул. Трубецкая, д. 8, корп. 2, Москва, 119991, Россия, khritinin_d_f@staff.sechenov.ru, ORCID: https://orcid.org/0000-0001-9107-2357

Заболевание, вызванное новой коронавирусной инфекцией является глобальной проблемой мирового здравоохранения не только по причине широкого распространения и высокой летальности, но и в связи с высоким риском возникновения постковидного синдрома (ПКС, Long-COVID-19), включающего в себя как соматические симптомы, так и психиатрические проявления (тревожность, депрессивные состояния, повышенную утомляемость, когнитивные нарушения, ПТСР и различные нарушения сна), оказывающие значительное влияние на качество жизни и трудоспособность пациентов, перенесших коронавирусную инфекцию. Целью данного обзора является анализ научной литературы для изучения гендерных особенностей течения постковидного синдрома и клинической картины данного состояния.

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В конце 2019 года в Китае (город Ухань) были зарегистрированы случаи тяжелой гриппоподобной инфекции, поражающей легкие. Сравнительно быстро китайские ученые выяснили, что причиной заболевания людей является коронавирус, родственный возбудителю атипичной пневмонии. Эти выводы были подтверждены и зарубежными исследователями. Новый вирус получил название SARS-CoV-2, а сама болезнь — COVID-19. Распространение данной инфекции за короткий период достигло масштабов пандемии, число случаев заражения продолжает расти и в настоящее время. Борьба с пандемией инфекции стала приоритетной задачей мирового здравоохранения [1].

По мере накопления клинического опыта и наблюдения за пациентами, перенесшими новую коронавирусную инфекцию с сохранением большого количества разнообразных симптомов после окончания острого периода, заболевания возникла необходимость внедрения новой терминологии. В связи с этим в различных научных источниках стали появляться определения: Long-COVID-19, long-haul-COVID-19, post-acute-COVID-19, chronic-COVID-19 и другие, отличающиеся сроками манифестации и клиническими проявлениями [2, 3].

Всемирная организация здравоохранения (ВОЗ) определяет термин постковидного синдрома как состояние, развившееся спустя 3 месяца после перенесенной коронавирусной инфекции, длящееся не менее 2 месяцев, которое не может быть объяснено другой патологией. Общие симптомы данного заболевания включают в себя повышенную утомляемость, одышку, когнитивные дисфункции и прочие состояния, оказывающие негативное влияние на повседневную жизнь индивида. Данные симптомы могут появляться, исчезать, сменять друг друга, а также затрагивать все больше систем и органов [4]. В катамнестических наблюдениях [5, 6] отражено, что постковидные симптомы могут сохраняться в течение длительного времени после выздоровления.

Стоит отметить, что постковидный синдром включен в Международную классификацию болезней 10‑го пересмотра (МКБ-10) под кодом U 09.9 «Состояние после COVID-19 неуточненное», включающее также постковидное состояние [7].

Для Цитирования:
Андреева Ирина Юрьевна, Дмитрий Федорович Хритинин, Гендерные особенности течения постковидного синдрома (обзор литературы). Вестник неврологии, психиатрии и нейрохирургии. 2025;12.
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