Myocardial disease of unknown etiology in pregnant women, accompanied by heart failure, was first described by B.A. Gouley in 1937. Heart failure after childbirth in African women was observed by H. Seftel and M. Susser. Peripartum cardiomyopathy is an idiopathic cardiomyopathy that manifests as heart failure against the background of systolic dysfunction of the left ventricle at the end of pregnancy or within 5 months after childbirth, which is one of the forms of dilated cardiomyopathy, associated with left ventricular failure and developing in initially healthy women without underlying cardiovascular disease.
To provide quality medical care to a patient, a physician needs accurate information about their health status, therefore, it is necessary for medical staff to correctly identify the patient. For this purpose, every medical organization needs to have an appropriate algorithm. The main stages of patient identification in a healthcare facility are presented in this article.
Provision of medical care to the population is strictly regulated at the state level by regulations, standards of medical care, clinical guidelines, and protocols. However, it is not always possible to fully implement all of the above documents at the level of a specific medical institution. Furthermore, to ensure the smooth organization of medical care, it is necessary to develop a patient pathway and detailed algorithms for the actions of medical personnel in any given critical situation. This function is fulfilled by local protocols, which are increasingly becoming part of the clinical work of medical institutions.
Targeted therapy is an innovative treatment approach based on the molecular and genetic characteristics of tumor growth. Unlike traditional methods, it targets specific molecules that play a key role in the growth and division of cancer cells, minimizing damage to healthy tissue. Key aspects include understanding the molecular mechanisms of cancer, the use of biomarkers, and high-tech developments such as monoclonal antibodies. Research in this area is rapidly advancing, opening up new prospects for fighting cancer. Combining targeted therapy with other treatment methods, developing new drugs, and more accurate diagnostic methods promise to improve treatment outcomes and make targeted therapy even more effective and personalized. The article explores the basic principles of targeted therapy, the mechanisms of action of the drugs used, examples of successful clinical trials, and the advantages and disadvantages of this approach.
Systemic connective tissue diseases primarily affect women of childbearing age, when pregnancy is a desired outcome. For a long time, autoimmune diseases were considered a contraindication to pregnancy. Today, these approaches have undergone significant changes. The course of the disease during pregnancy is variable, with both exacerbations and persistent remissions possible. This article presents general information on the basic principles of pregnancy and childbirth management in patients with connective tissue diseases.
Multiple myeloma (myeloma) is a malignant tumor of plasma cells (differentiated B lymphocytes that produce antibodies). It is a blood disorder classified as a paraproteinemic leukemia. The disease and tumor cell are named for the predominant localization of the process in the bone marrow. The etiology of myeloma remains unclear. The disease's prevalence is 3 cases per 100,000 population. This article presents two clinical cases of myeloma with polymorphic clinical manifestations.
Every year, the quantity and complexity of medical equipment in healthcare facilities grows. Simply purchasing expensive equipment for a clinic is not enough; it must be installed and integrated into the overall facility's operations, medical staff must be trained to operate it, it must be serviced, and components and consumables must be purchased. Technological management in the healthcare system addresses these issues. A well-designed medical management program in a healthcare facility improves the efficiency of medical care and ensures patient satisfaction with the medical service received.
October, like no other month, is rich in significant and memorable dates in medicine and healthcare. The first day of the month is traditionally celebrated as International Doctor's Day, October 10 is recognized as World Mental Health Day, and the 12th is World Arthritis Day. Ophthalmologists also celebrate their holiday in October – this year World Sight Day falls on October 13, and on October 16, resuscitation specialists celebrate World Anesthesia Day. However, remembering that the best thing in this world is children, today we will focus on the celebration of Child Health Day, which is celebrated in Russia on October 2.
