The problem of infection safety is extremely important in modern medicine. Determining accurate prevalence of nosocomial infections today is not possible, as this figure is significantly underestimated according to available statistical reports. Development and implementation of sanitary monitoring, organization of work of the Commission for infection control are important elements of improving the quality of medical care by the General practitioner.

Palliative care aims to achieve the best quality of life of patients suffering from life-threatening and incurable diseases, including HIV/AIDS and their families. Key elements of such care are relief of tolerability by patients all suffering — physical, mental, emotional and social, as well as creating conditions and providing support for people providing palliative care, to overcome the resulting emotional reactions and experiences.

To develop a system of measures aimed at improving the quality and efficiency of dispanserization of working population in 2014–2015 the study was conducted in three polyclinics of Makhachkala. Expert evaluation was subjected 387 cards of outpatients with chronic diseases, under the supervision of local doctors. Analyzed the content of 285 questionnaires collected from persons under medical surveillance. Expert assessment of the quality of dispanserization of working population revealed a number of defects: patients were observed irregularly on average, 32,4% of General practitioners, nearly half (48%) cases, local physicians and more than 2/3 (70,2%) cases by specialists. Every third patient (34,3%) the survey was conducted late, in 41,7% of cases — in full, at 39,9% of cases therapeutic measures were carried out defective. On the basis of research recommendations and suggestions for improving the quality of examination.

The increase in body temperature is one of the most common clinical symptoms faced by the General practitioner in their work. Quite often a cause of fever detected during the first visit to the doctor, but up to 30% of cases require an in-depth examination and differential diagnosis. Stepwise algorithms of examination of patients with fever presented in this article.

A study of the level of endothelial factors in the dynamics of physiological pregnancy with an interval of 4 weeks. The changes of endothelial factors in physiological pregnancy, demonstrate the predominance of vasodilating substances, in parallel, inhibiting excessive platelet aggregation. Characterized by the increase of levels of markers of endothelial damage with increasing gestational age, indicating that the development of the syndrome of endothelial dysfunction even at physiological course of pregnancy. Physiological pregnancy occurs on the background of stimulation and activation of the endothelium of the fetoplacental complex. In the period of 36–40 weeks, even in uncomplicated pregnancy develops endothelial dysfunction in the system «mother — placenta — fetus».

The paper proposed a mobile version of General practice through the application of functional spectral-dynamic diagnosis using complex medical the spectral-dynamic.

Aortic aneurysm is a disease involving an imminent threat to the life of the patient. Timely diagnosis of this disease allows to establish the diagnosis and to provide treatment in conditions that ensure the preservation of the life of the patient.

Spastic syndrome is a nonspecific reaction of the organism to external and internal stimuli, which is characterized by sudden and involuntary bouts of contractions of striated muscles. Convulsions appear in the background of pathological synchronized activity of groups of neurons. The cause of the seizures can serve as a serious disease of the Central nervous system such as meningitis, encephalitis, epilepsy, presence of tumor, head injuries, strokes, abscesses and bleeding in the brain. A seizure in an adult or child can occur when heavy metal poisoning in acute infections with severe course. The cause can also become hyperthermic condition or severe hypothermia. The algorithm is termination of convulsive syndrome is the main theme of this article.

The provision of medical care are strictly regulated at the state level regulations, standards of medical care, clinical guidelines and protocols. But not always at the level of individual medical institutions to fully implement all of the above documents. In addition, for efficient organization of medical care required of the patient and detailed algorithms of actions of the medical staff in one way or another critical situation. This function is performed by the local protocols, which are increasingly included in clinical work as a general practitioner.

Systemic lupus erythematosus — a systemic autoimmune disease. Medical care for patients with this pathology is based on normative documents of the Ministry of health of the Russian Federation. Timely diagnosis and adequate treatment can significantly improve prognosis, and reduce the rates of disability and mortality.

April 17, according to the international initiative of the who and the International Federation of anti-hemophilia world day of struggle with hemophilia. Every year on this day will join the action in many countries. The date itself, April 17, timed to the birthday of WFH founder Frank Schnabel and is celebrated since 1989. In Russia, the international hemophilia day is celebrated since 1996. According to some estimates, today the number of patients with hemophilia in the world is 400 thousand people (10 thousand men). In order to highlight this event is to attract the attention of international organizations, politicians, community and health workers to the problems that come to the fore in a patient with hemophilia, as well as raising awareness and knowledge of the population about this though infrequent but quite severe hereditary illness.