The article places particular emphasis on the theoretical foundations of datuming and dimensional chains. Datuming theory explains the principles of stable component fixation, ensuring positional stability and eliminating possible shifts during machining, which is critical for achieving specified accuracy. Dimension chain theory enables a systematic approach to tolerance distribution, minimizing error accumulation and ensuring design parameters meet design requirements. An examination of the application of these theoretical principles to process design demonstrates how scientific knowledge can be integrated into practical production, improving the quality of manufactured devices. The paper highlights current trends in the development of instrument-making technology, including the digitalization of production processes, the implementation of additive manufacturing, and automated quality control. Key issues related to materials, fixtures, and productivity improvements, as well as prospects for their solution, are analyzed. The practical significance of the work lies in the potential use of the obtained theoretical and technological information for the development and optimization of production processes in instrument-making enterprises. This helps reduce defects, increase productivity, and improve the performance characteristics of products.